Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy | PLOS ONE
![Nektar Therapeutics Announces Data Presentations for Its Immuno-Oncology Pipeline at the 2021 Society for Immunotherapy of Cancer (SITC) Annual Meeting Nektar Therapeutics Announces Data Presentations for Its Immuno-Oncology Pipeline at the 2021 Society for Immunotherapy of Cancer (SITC) Annual Meeting](https://mma.prnewswire.com/media/1390052/nektar_logo.jpg?p=twitter)
Nektar Therapeutics Announces Data Presentations for Its Immuno-Oncology Pipeline at the 2021 Society for Immunotherapy of Cancer (SITC) Annual Meeting
![Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist | Nature Communications Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist | Nature Communications](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-019-12901-3/MediaObjects/41467_2019_12901_Fig1_HTML.png)
Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist | Nature Communications
![JCM | Free Full-Text | Anti-PD-1 and Novel Combinations in the Treatment of Melanoma—An Update | HTML JCM | Free Full-Text | Anti-PD-1 and Novel Combinations in the Treatment of Melanoma—An Update | HTML](https://www.mdpi.com/jcm/jcm-09-00223/article_deploy/html/images/jcm-09-00223-g001.png)
JCM | Free Full-Text | Anti-PD-1 and Novel Combinations in the Treatment of Melanoma—An Update | HTML
![Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy | Nature Communications Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy | Nature Communications](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-020-14471-1/MediaObjects/41467_2020_14471_Fig1_HTML.png)
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy | Nature Communications
![NKTR-214 delivers a controlled, sustained, and biased signal through... | Download Scientific Diagram NKTR-214 delivers a controlled, sustained, and biased signal through... | Download Scientific Diagram](https://www.researchgate.net/profile/Michael-Eldon/publication/318216967/figure/fig1/AS:512906908844032@1499297944309/NKTR-214-delivers-a-controlled-sustained-and-biased-signal-through-the-IL2-receptor_Q640.jpg)
NKTR-214 delivers a controlled, sustained, and biased signal through... | Download Scientific Diagram
![PDF] NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models | Semantic Scholar PDF] NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/4b6d90c13629ffeaf1bdd2a19aa49043ea18b2f6/5-Figure2-1.png)
PDF] NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models | Semantic Scholar
![NKTR-214 synergizes with checkpoint blockade therapy a–c Mice bearing... | Download Scientific Diagram NKTR-214 synergizes with checkpoint blockade therapy a–c Mice bearing... | Download Scientific Diagram](https://www.researchgate.net/profile/Deborah-Charych/publication/338950005/figure/fig2/AS:958991244996621@1605652738529/NKTR-214-synergizes-with-checkpoint-blockade-therapy-a-c-Mice-bearing-sc-tumors-LLC.png)
NKTR-214 synergizes with checkpoint blockade therapy a–c Mice bearing... | Download Scientific Diagram
![A Study of NKTR-214 for Participants With Previously Untreated Inoperable or Metastatic Melanoma - Associazione Melanoma Italia Onlus A Study of NKTR-214 for Participants With Previously Untreated Inoperable or Metastatic Melanoma - Associazione Melanoma Italia Onlus](https://www.melanomaitalia.org/wp-content/uploads/2018/08/Schermata-2018-08-21-alle-10.10.56.jpg)
A Study of NKTR-214 for Participants With Previously Untreated Inoperable or Metastatic Melanoma - Associazione Melanoma Italia Onlus
![Parameterization of the mathematical model for NKTR-214 dynamics to... | Download Scientific Diagram Parameterization of the mathematical model for NKTR-214 dynamics to... | Download Scientific Diagram](https://www.researchgate.net/profile/Michael-Eldon/publication/318216967/figure/fig2/AS:512906909282304@1499297944399/Parameterization-of-the-mathematical-model-for-NKTR-214-dynamics-to-simulate_Q640.jpg)
Parameterization of the mathematical model for NKTR-214 dynamics to... | Download Scientific Diagram
![Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy | Nature Communications Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy | Nature Communications](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-020-14471-1/MediaObjects/41467_2020_14471_Fig5_HTML.png)
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy | Nature Communications
![NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8<sup>+</sup> T cell responses capable of curing multi-focal cancer. - Abstract - Europe PMC NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8<sup>+</sup> T cell responses capable of curing multi-focal cancer. - Abstract - Europe PMC](https://europepmc.org/articles/PMC7252958/bin/jitc-2019-000464f03.jpg)